HitPredict

Interactor 1: SRC64 (P00528)
Tyrosine-protein kinase Src64B (Dsrc64) (EC 2.7.10.2)
Gene: Src64B

Interactor 2: Q9VJA1 (Q9VJA1)
Suppressor of cytokine signaling SOCS36E (Suppressor of cytokine signaling at 36E, isoform A) (Suppressor of cytokine signaling at 36E, isoform C)
Gene: Socs36E

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH2, SH2~SH2, SH2~SOCS_box, SH2~SH3_1
Common GO terms	GO:0007616 - long-term memory
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 552 Dm			1 633
+	Dm
		337688 SRC64_DROME (1-552): 0: 592: 100.00		Q8INY1_DROME (1-633): 0: 669: 100.00
+	Hs
		146582 YES_HUMAN (5-549): 0: 565: 45.42		SOCS2_HUMAN (431-613): 3.83e-51: 177: 28.28
+	Hs
		433231 YES_HUMAN (5-549): 0: 565: 45.42		SRC_HUMAN (307-590): 1.24e-46: 174: 15.49
+	Hs
		411946 YES_HUMAN (5-549): 0: 565: 45.42		FYN_HUMAN (351-620): 2.97e-45: 170: 15.55
+	Dm
		186276 SRC64_DROME (1-552): 0: 592: 100.00		O18683_DROME (431-576): 6.06e-35: 140: 22.82
+	Hs
		146668 YES_HUMAN (5-549): 0: 565: 45.42		SOCS7_HUMAN (285-612): 4.31e-43: 165: 21.17
+	Mm
		763403 FYN_MOUSE (31-549): 0: 551: 45.98		NCK1_MOUSE (305-557): 1.46e-49: 178: 16.99
+	Hs
		411552 YES_HUMAN (5-549): 0: 565: 45.42		LCK_HUMAN (384-628): 4.78e-43: 163: 13.89
+	Hs
		147377 YES_HUMAN (5-549): 0: 565: 45.42		SOCS3_HUMAN (435-610): 1.13e-44: 160: 24.20
+	Hs
		433215 YES_HUMAN (5-549): 0: 565: 45.42		YES_HUMAN (314-628): 3.82e-41: 159: 14.46
+	Hs
		411936 FYN_HUMAN (31-549): 0: 550: 45.79		FYN_HUMAN (351-620): 2.97e-45: 170: 15.55
+	Hs
		181770 YES_HUMAN (5-549): 0: 565: 45.42		SOCS1_HUMAN (450-613): 5.94e-42: 152: 25.61
+	Hs
		411545 FYN_HUMAN (31-549): 0: 550: 45.79		LCK_HUMAN (384-628): 4.78e-43: 163: 13.89
+	Hs
		181765 FYN_HUMAN (31-549): 0: 550: 45.79		SOCS1_HUMAN (450-613): 5.94e-42: 152: 25.61
+	Dm
		337676 SRC64_DROME (1-552): 0: 592: 100.00		GRAP_DROME (461-596): 2.49e-15: 77.2: 21.17
+	Hs
		433433 YES_HUMAN (5-549): 0: 565: 45.42		P55G_HUMAN (470-582): 3.84e-19: 92.6: 21.55
+	Hs
		129164 FYN_HUMAN (31-549): 0: 550: 45.79		P85B_HUMAN (464-570): 1.53e-22: 104: 24.55
+	Hs
		433263 YES_HUMAN (5-549): 0: 565: 45.42		P85A_HUMAN (465-573): 8.82e-17: 86.4: 23.21
+	Mm
		643066 FYN_MOUSE (31-549): 0: 551: 45.98		P85A_MOUSE (465-573): 8.82e-17: 86.4: 23.21