HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.614

The method score is based on:

Property Details
Experiments 24412244, 35384245
Identification Methods two hybrid, affinity chromatography technology, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007435 - salivary gland morphogenesis
and 18 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 390
+ Hs
+ Hs
+ Hs
+ Rn

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Last updated: 15 Jul 2024