HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23956138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 444
+	Hs
		337782 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		338386 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TBB3_HUMAN (1-444): 0: 714: 91.44
+	Hs
		338266 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TBB4B_HUMAN (1-427): 0: 713: 98.60
+	Hs
		338407 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TBB2A_HUMAN (1-430): 0: 709: 96.28
+	Hs
		338925 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TBB6_HUMAN (1-433): 0: 708: 93.07
+	Hs
		383959 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		TBB6_HUMAN (1-433): 0: 708: 93.07
+	Hs
		428019 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		601930 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		TBB8_HUMAN (1-427): 0: 702: 90.16
+	Hs
		428109 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		872631 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		TBB4B_HUMAN (1-427): 0: 713: 98.60
+	Hs
		872702 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		TBB2B_HUMAN (1-430): 0: 712: 96.74
+	Hs
		381152 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		TBB4A_HUMAN (1-427): 0: 709: 100.00
+	Hs
		428222 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		872701 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		TBB6_HUMAN (1-433): 0: 708: 93.07
+	Hs
		1072512 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		TBB8_HUMAN (1-427): 0: 702: 90.16
+	Hs
		411272 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Gg
		94429 KSYK_CHICK (718-961): 1.71e-55: 206: 41.30		TBB7_CHICK (1-429): 0: 714: 97.44
+	Hs
		428078 KSYK_HUMAN (716-961): 1.13e-53: 201: 41.70		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		428077 ZAP70_HUMAN (718-961): 5.57e-53: 199: 39.59		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		537737 INSRR_HUMAN (352-656): 3.99e-25: 115: 20.90		TBB3_HUMAN (1-444): 0: 714: 91.44