Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: G3P (P04406)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-)
Gene: GAPDH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.734

The method score is based on:

Property Details
Experiments 25402006, 24658140, 23956138, 16799092, 20029029, unassigned2173
Identification Methods two hybrid, protein complementation assay, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, ubiquitin reconstruction
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0031965 - nuclear membrane
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 335
+ Hs
+ Hs
+ Rn
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024