Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 0.60 | 0.561 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17115032 |
| Identification Methods | affinity chromatography technology, enzymatic study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0019899 - enzyme binding GO:0045739 - positive regulation of DNA repair GO:0045740 - positive regulation of DNA replication and 2 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
