Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 24780295, 28065597, 25261371
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0050730 - regulation of peptidyl-tyrosine phosphorylation
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 710
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024