Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 24189400
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0016323 - basolateral plasma membrane
and 4 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 1241
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

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Last updated: 15 Jul 2024