Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: NOS2 (P35228)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.534

The method score is based on:

Property Details
Experiments 15950906
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005516 - calmodulin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007623 - circadian rhythm
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 1153
+ Rn

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Last updated: 15 Jul 2024