HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.735

The method score is based on:

Property Details
Experiments 32377695, 34761192, 15701692, 21226813, 19109251, 9049247, 16499958
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0009925 - basal plasma membrane
GO:0016020 - membrane
GO:0016324 - apical plasma membrane
and 2 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 896
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024