Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: CAMLG (P49069)
Guided entry of tail-anchored proteins factor CAMLG (Calcium signal-modulating cyclophilin ligand)
Gene: CAMLG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.697

The method score is based on:

Property Details
Experiments 25402006, 24658140, 12919676, unassigned2173
Identification Methods two hybrid, protein complementation assay, affinity chromatography technology, ubiquitin reconstruction, luminescence based mammalian interactome mapping
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0007165 - signal transduction
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0016020 - membrane
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 296
+ Hs

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Last updated: 15 Jul 2024