HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: EFTU (P49411)
Elongation factor Tu, mitochondrial (EF-Tu) (P43)
Gene: TUFM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	28065597, 24189400
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 455
+	Hs
		338263 EGFR_HUMAN (1-1210): 0: 1241: 100.00		EF1A1_HUMAN (54-442): 3.32e-133: 393: 28.73
+	Hs
		383692 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		EFTU_HUMAN (1-455): 1.08e-173: 496: 100.00
+	Hs
		601850 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		EFTU_HUMAN (1-455): 1.08e-173: 496: 100.00
+	Rn
		544806 INSR_RAT (579-1032): 2.5e-106: 367: 23.66		EF1A1_RAT (54-442): 3.86e-133: 393: 28.73
+	Hs
		827353 ACK1_HUMAN (691-967): 4.54e-56: 214: 39.58		EFTU_HUMAN (1-455): 1.08e-173: 496: 100.00
+	Hs
		435606 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		EF1A1_HUMAN (54-442): 3.32e-133: 393: 28.73