HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: OCLN (Q16625)
Occludin
Gene: OCLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016324 - apical plasma membrane GO:0030054 - cell junction GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 522
+	Hs
		383834 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		OCLN_HUMAN (1-522): 0: 757: 100.00
+	Hs
		872656 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		OCLN_HUMAN (1-522): 0: 757: 100.00
+	Hs
		665611 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		OCLN_HUMAN (1-522): 0: 757: 100.00
+	Hs
		1072508 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		OCLN_HUMAN (1-522): 0: 757: 100.00
+	Hs
		665255 EPHA2_HUMAN (665-1016): 5.77e-117: 389: 32.79		OCLN_HUMAN (1-522): 0: 757: 100.00
+	Hs
		411400 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		OCLN_HUMAN (1-522): 0: 757: 100.00
+	Rn
		192647 FAK1_RAT (716-991): 6.81e-54: 207: 37.68		OCLN_RAT (1-522): 0: 747: 87.57