Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: LRRK1 (Q38SD2)
Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)
Gene: LRRK1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.74 | 1.00 | 0.861 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | COR~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase |
Common GO terms | GO:0005524 - ATP binding GO:0016020 - membrane GO:0090263 - positive regulation of canonical Wnt signaling pathway |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024