Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.55 | 0.458 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31959764 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0019901 - protein kinase binding GO:0030307 - positive regulation of cell growth GO:0043066 - negative regulation of apoptotic process GO:0051896 - regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
