Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: DP13B (Q8NEU8)
DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)
Gene: APPL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35384245
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0005634 - nucleus
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0010008 - endosome membrane
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 664
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024