Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: PDC6I (Q8WUM4)
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)
Gene: PDCD6IP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.729

The method score is based on:

Property Details
Experiments 25402006, 24658140, 15456872, 12771190, unassigned2173, 15557335
Identification Methods two hybrid, protein complementation assay, affinity chromatography technology, ubiquitin reconstruction, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0005925 - focal adhesion
GO:0016020 - membrane
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 868
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024