HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: S39A7 (Q92504)
Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)
Gene: SLC39A7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	28065597, 35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 469
+	Hs
		383904 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		S39A7_HUMAN (1-469): 2.05e-103: 318: 100.00
+	Hs
		338692 EGFR_HUMAN (1-1210): 0: 1241: 100.00		S39AB_HUMAN (129-467): 4.29e-49: 173: 15.04
+	Hs
		665637 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		S39A7_HUMAN (1-469): 2.05e-103: 318: 100.00
+	Hs
		1072564 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		S39A7_HUMAN (1-469): 2.05e-103: 318: 100.00