HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: SEPT8 (Q92599)
Septin-8
Gene: SEPTIN8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 483
+	Hs
		383907 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		339064 EGFR_HUMAN (1-1210): 0: 1241: 100.00		SEP10_HUMAN (1-429): 0: 582: 72.96
+	Hs
		338417 EGFR_HUMAN (1-1210): 0: 1241: 100.00		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		339093 EGFR_HUMAN (1-1210): 0: 1241: 100.00		SEPT9_HUMAN (8-319): 1.86e-155: 455: 39.81
+	Hs
		339089 EGFR_HUMAN (1-1210): 0: 1241: 100.00		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40
+	Hs
		383800 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		434254 RET_HUMAN (420-1058): 5.61e-129: 425: 22.69		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		665639 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		411459 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		665674 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		SEP10_HUMAN (1-429): 0: 582: 72.96
+	Hs
		665599 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		1048994 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		SEPT6_HUMAN (1-429): 0: 576: 76.22
+	Hs
		665678 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		SEPT9_HUMAN (8-319): 1.86e-155: 455: 39.81
+	Hs
		665677 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40
+	Hs
		435711 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		SEPT8_HUMAN (1-483): 0: 719: 100.00
+	Hs
		435787 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		SEP10_HUMAN (1-429): 0: 582: 72.96
+	Hs
		435638 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		SEPT6_HUMAN (1-429): 0: 576: 76.22