HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: PCX1 (Q96RV3)
Pecanex-like protein 1 (Pecanex homolog protein 1)
Gene: PCNX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28065597
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1210 Hs			1 2341
+	Hs
		337875 EGFR_HUMAN (1-1210): 0: 1241: 100.00		MUC1_HUMAN (83-989): 7.15e-36: 151: 6.65
+	Hs
		338878 EGFR_HUMAN (1-1210): 0: 1241: 100.00		MUC4_HUMAN (137-993): 4.7e-21: 104: 9.80
+	Hs
		338321 EGFR_HUMAN (1-1210): 0: 1241: 100.00		ZO1_HUMAN (102-981): 5.88e-21: 103: 10.79
+	Hs
		338874 EGFR_HUMAN (1-1210): 0: 1241: 100.00		MINT_HUMAN (47-991): 7.3e-15: 83.8: 7.91
+	Hs
		339003 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TENS1_HUMAN (234-979): 2.03e-13: 78.8: 8.51
+	Hs
		338965 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TARA_HUMAN (433-1001): 4.04e-13: 77.6: 8.20
+	Hs
		204894 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TGON2_HUMAN (363-697): 1.68e-09: 64.8: 18.84
+	Hs
		554307 ERBB4_HUMAN (1-1199): 0: 1137: 49.46		MUC1_HUMAN (83-989): 7.15e-36: 151: 6.65
+	Hs
		383583 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		MUC1_HUMAN (83-989): 7.15e-36: 151: 6.65
+	Hs
		1071005 ERBB4_HUMAN (1-1199): 0: 1137: 49.46		MUC4_HUMAN (137-993): 4.7e-21: 104: 9.80
+	Hs
		554266 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		MUC1_HUMAN (83-989): 7.15e-36: 151: 6.65
+	Hs
		1071015 ERBB4_HUMAN (1-1199): 0: 1137: 49.46		TENS1_HUMAN (234-979): 2.03e-13: 78.8: 8.51
+	Hs
		383946 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		MUC4_HUMAN (137-993): 4.7e-21: 104: 9.80
+	Hs
		383987 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		TENS1_HUMAN (234-979): 2.03e-13: 78.8: 8.51
+	Hs
		601984 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		MUC4_HUMAN (137-993): 4.7e-21: 104: 9.80
+	Hs
		204915 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		TGON2_HUMAN (363-697): 1.68e-09: 64.8: 18.84
+	Hs
		602002 ERBB3_HUMAN (1-1210): 0: 1080: 40.95		TENS1_HUMAN (234-979): 2.03e-13: 78.8: 8.51
+	Hs
		205216 EPHA4_HUMAN (660-1016): 3.35e-120: 398: 31.52		TGON2_HUMAN (363-697): 1.68e-09: 64.8: 18.84
+	Hs
		205079 EPHB2_HUMAN (642-1067): 4.6e-119: 397: 28.76		TGON2_HUMAN (363-697): 1.68e-09: 64.8: 18.84
+	Hs
		205078 EPHA2_HUMAN (665-1016): 5.77e-117: 389: 32.79		TGON2_HUMAN (363-697): 1.68e-09: 64.8: 18.84