HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25754235
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 494
+	Hs
		338364 EGFR_HUMAN (1-1210): 0: 1241: 100.00		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		338010 EGFR_HUMAN (1-1210): 0: 1241: 100.00		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		338171 EGFR_HUMAN (1-1210): 0: 1241: 100.00		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Hs
		338906 EGFR_HUMAN (1-1210): 0: 1241: 100.00		Q9BPW0_HUMAN (242-391): 8.91e-09: 59.7: 31.79
+	Hs
		383642 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		383889 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35
+	Hs
		383952 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		Q9BPW0_HUMAN (242-391): 8.91e-09: 59.7: 31.79
+	Hs
		1028051 EPHA7_HUMAN (653-1072): 5.04e-118: 392: 27.23		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		411373 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Rn
		193482 INSR_RAT (579-1032): 2.5e-106: 367: 23.66		STIP1_RAT (8-208): 3.19e-12: 70.7: 12.34
+	Hs
		684651 FAK1_HUMAN (716-991): 1.58e-53: 206: 37.68		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		435627 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83