HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: UGGG1 (Q9NYU2)
UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1)
Gene: UGGT1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	25754235, 35384245, 34591612
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 1555
+	Hs
		339054 EGFR_HUMAN (1-1210): 0: 1241: 100.00		UGGG2_HUMAN (25-1540): 0: 2098: 54.83
+	Hs
		411510 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		UGGG1_HUMAN (1-1555): 0: 2306: 100.00
+	Hs
		411509 INSR_HUMAN (451-1026): 9.86e-109: 374: 20.87		UGGG2_HUMAN (25-1540): 0: 2098: 54.83
+	Hs
		435782 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		UGGG1_HUMAN (1-1555): 0: 2306: 100.00
+	Hs
		435781 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		UGGG2_HUMAN (25-1540): 0: 2098: 54.83