HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: XPO7 (Q9UIA9)
Exportin-7 (Exp7) (Ran-binding protein 16)
Gene: XPO7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24797263, 23956138
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 1087
+	Hs
		162322 EGFR_HUMAN (1-1210): 0: 1241: 100.00		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		162768 ERBB4_HUMAN (1-1199): 0: 1137: 49.46		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		162330 ERBB2_HUMAN (5-1200): 0: 1111: 48.49		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		338952 EGFR_HUMAN (1-1210): 0: 1241: 100.00		XPO4_HUMAN (4-1073): 0: 665: 17.43
+	Mm
		1322252 FAK2_MOUSE (716-974): 4.22e-52: 201: 37.64		XPO7_MOUSE (1-1087): 0: 1231: 99.45
+	Hs
		339000 EGFR_HUMAN (1-1210): 0: 1241: 100.00		XPO5_HUMAN (6-239): 7.13e-43: 172: 15.14
+	Hs
		338865 EGFR_HUMAN (1-1210): 0: 1241: 100.00		XPO6_HUMAN (1-1083): 1.49e-33: 142: 11.62
+	Hs
		297142 EGFR_HUMAN (1-1210): 0: 1241: 100.00		IPO13_HUMAN (8-726): 5.88e-15: 81.8: 12.82
+	Hs
		207868 EGFR_HUMAN (1-1210): 0: 1241: 100.00		XPOT_HUMAN (12-229): 2.94e-11: 69.9: 13.84
+	Hs
		339200 EGFR_HUMAN (1-1210): 0: 1241: 100.00		TNPO3_HUMAN (8-547): 6.77e-10: 65.6: 13.48
+	Hs
		162344 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		435766 IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47		XPO5_HUMAN (6-239): 7.13e-43: 172: 15.14