Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: ERRFI (Q9UJM3)
ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (MIG-6)
Gene: ERRFI1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.764 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26280531, 28842482, 19815557, 24189400, 28065597, 18046415, 25754235, 35384245, 36736316, 19531499, 18271526, 23956138, 24797263, 23273428, 18776048, 34591642 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, enzymatic study, classical fluorescence spectroscopy, anti bait coimmunoprecipitation, pull down, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007173 - epidermal growth factor receptor signaling pathway GO:0019901 - protein kinase binding and 2 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
