Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: DP13A (Q9UKG1)
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)
Gene: APPL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 35384245, 16273093
Identification Methods proximity labelling technology, unspecified method, protein array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 709
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Last updated: 15 Jul 2024