HitPredict

Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: TLN1 (Q9Y490)
Talin-1
Gene: TLN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16273093
Identification Methods unspecified method, protein array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_M~PK_Tyr_Ser-Thr
Common GO terms GO:0005178 - integrin binding
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0009986 - cell surface
GO:0032587 - ruffle membrane
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024