HitPredict

Interactor 1: MOS (P00540)
Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (Oocyte maturation factor mos) (Proto-oncogene c-Mos)
Gene: MOS

Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	32707033, 22939624
Identification Methods	affinity chromatography technology, pull down, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 724
+	Hs
		339217 MOS_HUMAN (1-346): 1.45e-130: 378: 100.00		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		437960 CSK_HUMAN (49-342): 3.46e-26: 110: 31.67		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		438113 M3K12_HUMAN (55-345): 8.25e-26: 110: 28.08		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		431619 CSK_HUMAN (49-342): 3.46e-26: 110: 31.67		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		431787 M3K12_HUMAN (55-345): 8.25e-26: 110: 28.08		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Zm
		8229 A0A1D6ELX5_MAIZE (55-345): 2.62e-92: 293: 28.23		A0A1D6LMW9_MAIZE (5-693): 0: 852: 46.66
+	Hs
		339257 MOS_HUMAN (1-346): 1.45e-130: 378: 100.00		Q6PK50_HUMAN (1-350): 0: 618: 99.71
+	At
		287794 O82754_ARATH (53-341): 1.12e-24: 107: 28.67		HS905_ARATH (1-724): 0: 885: 43.56