HitPredict

Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	24374311, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 298 Sc			1 613
+	Sc
		339666 CDK1_YEAST (1-298): 1.93e-142: 404: 100.00		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Sc
		510173 PHO85_YEAST (6-297): 2.21e-126: 364: 52.67		SSB1_YEAST (1-613): 0: 1128: 100.00
+	Sc
		565620 PHO85_YEAST (6-297): 2.21e-126: 364: 52.67		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Hs
		503460 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		503902 CDK3_HUMAN (5-295): 4.65e-147: 416: 63.92		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		713942 CDK3_HUMAN (5-295): 4.65e-147: 416: 63.92		HS71L_HUMAN (5-612): 0: 896: 59.34
+	At
		612295 CDKA1_ARATH (5-297): 3.44e-139: 396: 61.22		HS701_ARATH (1-612): 0: 893: 57.79
+	Mm
		509463 CDK1_MOUSE (5-297): 2.56e-140: 399: 59.39		HSP72_MOUSE (4-612): 0: 888: 59.64