HitPredict

Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: CKS1 (P20486)
Cyclin-dependent kinases regulatory subunit (Cell division control protein CKS1)
Gene: CKS1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 2664468, 11283351, 10655498, 11805837, 11805826, 24374311, 11527976, 10323869, 16429126, 17634282, 18563728, 19647054, 20489023, 16319894, 10871279, 10913169, 37968396, 23825181
Identification Methods coimmunoprecipitation, two hybrid pooling approach, two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, biochemical, enzymatic study, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CKS~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0042393 - histone binding
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 298
Sc

1 150
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+ Ce
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Last updated: 15 Jul 2024