HitPredict

Interactor 1: CDK1 (P00546)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (Cell division control protein 28) (Cell division protein kinase 1)
Gene: CDC28

Interactor 2: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	10323869, 16429126
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 298 Sc			1 467
+	Hs
		625301 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		PRS8_HUMAN (81-464): 6.1e-121: 361: 44.53
+	Hs
		625315 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		PRS10_HUMAN (81-463): 5.38e-120: 358: 42.04
+	Sc
		339767 CDK1_YEAST (1-298): 1.93e-142: 404: 100.00		PRS10_YEAST (29-465): 2.46e-123: 367: 37.07
+	Sc
		339798 CDK1_YEAST (1-298): 1.93e-142: 404: 100.00		PRS8_YEAST (142-452): 2.32e-105: 320: 51.77
+	Hs
		625268 CDK2_HUMAN (5-297): 1.27e-155: 437: 62.12		TERA_HUMAN (33-442): 6.46e-80: 265: 28.13
+	Hs
		414839 CDK1_HUMAN (5-297): 1.32e-141: 402: 59.73		TERA_HUMAN (33-442): 6.46e-80: 265: 28.13