HitPredict

Interactor 1: KPYK1 (P00549)
Pyruvate kinase 1 (PK 1) (EC 2.7.1.40) (cell division cycle protein 19)
Gene: CDC19

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31399574, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 500 Sc			1 705
+	Hs
		437856 KPYM_HUMAN (2-500): 0: 741: 50.10		HS90B_HUMAN (5-705): 0: 1022: 61.15
+	Hs
		431489 KPYM_HUMAN (2-500): 0: 741: 50.10		HS90A_HUMAN (4-705): 0: 1013: 60.67
+	Sc
		339945 KPYK1_YEAST (1-500): 0: 712: 100.00		HSP82_YEAST (1-705): 0: 968: 95.63
+	Ca
		804464 KPYK_CANAL (2-499): 0: 704: 72.40		HSP90_CANAL (4-705): 0: 953: 82.36
+	Sc
		366596 KPYK2_YEAST (2-500): 0: 667: 70.94		HSP82_YEAST (1-705): 0: 968: 95.63