Interactor 1: KPYK1 (P00549)
Pyruvate kinase 1 (PK 1) (EC 2.7.1.40) (cell division cycle protein 19)
Gene: CDC19

Interactor 2: KPYK2 (P52489)
Pyruvate kinase 2 (PK 2) (EC 2.7.1.40)
Gene: PYK2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 37968396, 16429126
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK~PK, PK~PK_C, PK_C~PK_C
Common GO terms GO:0000287 - magnesium ion binding
GO:0004743 - pyruvate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006090 - pyruvate metabolic process
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 500
Sc

1 506
+ Hs
+ Hs
+ Oc
+ Sc
+ Ce
+ Ce
+ Ce
+ Ce
+ Ec
+ At
+ At
+ Zm
+ Ec

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Last updated: 15 Jul 2024