Interactor 1: FA10 (P00742)
Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor) [Cleaved into: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain]
Gene: F10
Interactor 2: FA7 (P08709)
Coagulation factor VII (EC 3.4.21.21) (Proconvertin) (Serum prothrombin conversion accelerator) (SPCA) (Eptacog alfa) [Cleaved into: Factor VII light chain; Factor VII heavy chain]
Gene: F7
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11560488 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~EGF, EGF~FXa_inhibition, EGF~Trypsin, FXa_inhibition~FXa_inhibition, FXa_inhibition~Trypsin, Trypsin~Trypsin |
| Common GO terms | GO:0002690 - positive regulation of leukocyte chemotaxis GO:0004252 - serine-type endopeptidase activity GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0005615 - extracellular space and 6 others more... |
| Homologous interactions | 8 |
Homologous interactions
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Last updated: 15 Jul 2024
