Interactor 1: FA12 (P00748)
Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)]
Gene: F12
Interactor 2: FA12 (P00748)
Coagulation factor XII (EC 3.4.21.38) (Hageman factor) (HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Coagulation factor XIIa light chain (Beta-factor XIIa part 2)]
Gene: F12
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18838541 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~EGF, EGF~fn1, EGF~Trypsin, fn1~fn1, fn1~fn2, fn2~fn2, Kringle~Kringle, Kringle~Trypsin, Trypsin~Trypsin |
| Common GO terms | GO:0002353 - plasma kallikrein-kinin cascade GO:0002542 - Factor XII activation GO:0004252 - serine-type endopeptidase activity GO:0005509 - calcium ion binding GO:0005576 - extracellular region and 17 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
