HitPredict

Interactor 1: UROK (P00749)
Urokinase-type plasminogen activator (U-plasminogen activator) (uPA) (EC 3.4.21.73) [Cleaved into: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B]
Gene: PLAU

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.561

Property	Details
Experiments	35013218, 21988832
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 454
+	Hs
		345712 TRY1_HUMAN (172-427): 1.3e-97: 294: 33.98		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379405 HABP2_HUMAN (32-429): 8.08e-126: 377: 35.59		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		347119 TM11A_HUMAN (158-423): 2.55e-37: 142: 34.91		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346072 TRY3_HUMAN (178-420): 2.67e-36: 137: 37.71		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		378915 TRY1_HUMAN (172-427): 1.3e-97: 294: 33.98		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		341519 TPA_HUMAN (18-155): 1.52e-29: 122: 45.07		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		345823 HGF_HUMAN (69-155): 7.35e-12: 69.3: 26.14		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379066 TRY3_HUMAN (178-420): 2.67e-36: 137: 37.71		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		341523 TPA_HUMAN (18-155): 1.52e-29: 122: 45.07		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		341335 PLMN_HUMAN (68-153): 3.16e-13: 73.5: 31.03		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40