Interactor 1: UROK (P00749)
Urokinase-type plasminogen activator (U-plasminogen activator) (uPA) (EC 3.4.21.73) [Cleaved into: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B]
Gene: PLAU
Interactor 2: UPAR (Q03405)
Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87)
Gene: PLAUR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 0.90 | 0.895 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19017363, 11501527, 33961781, 16879932, 18376415, 24457100 |
| Identification Methods | affinity chromatography technology, pull down, molecular sieving, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Kringle~UPAR_LY6 |
| Common GO terms | GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0006935 - chemotaxis GO:0007165 - signal transduction and 10 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
