Interactor 1: TPA (P00750)
Tissue-type plasminogen activator (t-PA) (t-plasminogen activator) (tPA) (EC 3.4.21.68) (Alteplase) (Reteplase) [Cleaved into: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B]
Gene: PLAT
Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF~EGF, EGF~EGF_CA, EGF~fn1, EGF~Trypsin |
| Common GO terms | GO:0005576 - extracellular region GO:0009986 - cell surface |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
