Interactor 1: TPA (P00750)
Tissue-type plasminogen activator (t-PA) (t-plasminogen activator) (tPA) (EC 3.4.21.68) (Alteplase) (Reteplase) [Cleaved into: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B]
Gene: PLAT

Interactor 2: PDGFC (Q9NRA1)
Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)]
Gene: PDGFC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 22035541
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CUB~Kringle
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0009986 - cell surface
GO:0048008 - platelet-derived growth factor receptor signaling pathway
GO:0070062 - extracellular exosome
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 562
Hs

1 345
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024