HitPredict

Interactor 1: ENO1 (P00924)
Enolase 1 (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase 1) (2-phosphoglycerate dehydratase 1)
Gene: ENO1

Interactor 2: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31399574, 37295430, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 437 Sc			1 705
+	Hs
		417110 ENOA_HUMAN (1-433): 0: 731: 63.28		HS90B_HUMAN (5-705): 0: 1022: 61.15
+	Sc
		342602 ENO1_YEAST (1-437): 0: 700: 100.00		HSP82_YEAST (1-705): 0: 968: 95.63
+	Sc
		366460 ERR3_YEAST (1-437): 0: 688: 67.96		HSP82_YEAST (1-705): 0: 968: 95.63
+	Sc
		342842 ENO2_YEAST (1-437): 0: 665: 95.20		HSC82_YEAST (1-705): 0: 977: 100.00
+	Ca
		674996 ENO1_CANAL (4-437): 0: 681: 77.75		HSP90_CANAL (4-705): 0: 953: 82.36
+	Sc
		342800 ENO2_YEAST (1-437): 0: 665: 95.20		HSP82_YEAST (1-705): 0: 968: 95.63
+	Hs
		417134 ENOA_HUMAN (1-433): 0: 731: 63.28		ENPL_HUMAN (3-680): 0: 893: 47.10