Interactor 1: SYA (P00957)
Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)
Gene: alaS

Interactor 2: SYA (P00957)
Alanine--tRNA ligase (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)
Gene: alaS

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments unassigned104, 16858726
Identification Methods comigration in non denaturing gel electrophoresis, blue native page
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DHHA1~DHHA1, tRNA-synt_2c~tRNA-synt_2c, tRNA-synt_2c~tRNA_SAD
Common GO terms GO:0000049 - tRNA binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0002161 - aminoacyl-tRNA editing activity
GO:0002196 - Ser-tRNA(Ala) hydrolase activity
GO:0004813 - alanine-tRNA ligase activity
and 7 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 876
Ec

1 876
+ Sc
+ Af
+ Hs
+ Sc
+ Hs
+ Hs
+ Ec

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Last updated: 15 Jul 2024