HitPredict

Interactor 1: SYMC (P00958)
Methionine--tRNA ligase, cytoplasmic (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)
Gene: MES1

Interactor 2: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37845327, 19536198
Identification Methods	proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 751 Sc			1 352
+	Sc
		343805 SYMC_YEAST (1-751): 0: 730: 100.00		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		607859 SYMM_YEAST (200-710): 4.13e-111: 350: 17.64		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		430750 SYV_YEAST (168-380): 1.25e-45: 178: 14.35		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00
+	Sc
		450282 SYIC_YEAST (168-347): 2.45e-39: 158: 13.93		MAS5_YEAST (1-352): 1.41e-111: 332: 28.13
+	Sc
		450280 SYIC_YEAST (168-347): 2.45e-39: 158: 13.93		SIS1_YEAST (1-352): 6.96e-105: 313: 100.00
+	Ec
		343734 SYI_ECOLI (361-709): 1.08e-27: 122: 14.57		DNAJ_ECOLI (2-351): 3.01e-107: 320: 26.48