Interactor 1: CARB (P00968)
Carbamoyl phosphate synthase large chain (EC 6.3.4.16) (EC 6.3.5.5) (Carbamoyl phosphate synthetase ammonia chain)
Gene: CARB

Interactor 2: CARA (P0A6F1)
Carbamoyl phosphate synthase small chain (EC 6.3.5.5) (Carbamoyl phosphate synthetase glutamine chain)
Gene: CARA

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 29176613, 24561554, 19402753, 22841294, 9636022, 10029528, 12130656, 15690043, 23582331, 10428826
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification, ion mobility mass spectrometry of complexes, x-ray crystallography, mass spectrometry studies of complexes, pull down, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CPSase_L_D2~CPSase_sm_chain, CPSase_L_D2~GATase, CPSase_L_D3~CPSase_sm_chain
Common GO terms GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005951 - carbamoyl-phosphate synthase complex
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1073
Ec

1 382
+ Hs
+ At
+ Nv
+ Sc
+ Sc
+ Dm
+ Sc
+ Pf

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024