HitPredict

Interactor 1: A1AT (P01009)
Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)]
Gene: SERPINA1

Interactor 2: SARAF (Q96BY9)
Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (HBV X-transactivated gene 3 protein) (HBV XAg-transactivated protein 3) (Protein FOAP-7) (Transmembrane protein 66)
Gene: SARAF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 339
+	Hs
		344321 AACT_HUMAN (20-417): 3e-164: 469: 43.56		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		1218291 SPA12_HUMAN (1-418): 1e-153: 442: 38.28		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		1203163 SPA9_HUMAN (3-417): 6.59e-153: 440: 39.67		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		397056 PAI2_HUMAN (50-415): 9.67e-149: 430: 28.88		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		820360 SPB4_HUMAN (48-415): 1.16e-148: 428: 32.31		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		668010 SPB3_HUMAN (48-415): 1.73e-147: 425: 31.03		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		839502 SPB8_HUMAN (48-415): 1.46e-145: 420: 31.48		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		1286068 SPB13_HUMAN (48-415): 1.51e-143: 415: 28.65		SARAF_HUMAN (1-339): 0: 573: 100.00
+	Hs
		271885 SPB7_HUMAN (48-415): 3.68e-139: 404: 26.96		SARAF_HUMAN (1-339): 0: 573: 100.00