HitPredict

Interactor 1: AACT (P01011)
Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less]
Gene: SERPINA3

Interactor 2: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 423 Hs			1 321
+	Hs
		344199 A1AT_HUMAN (9-422): 3.46e-159: 457: 43.65		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		437221 CBG_HUMAN (35-420): 1.24e-147: 426: 46.89		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		820323 SPB4_HUMAN (48-420): 6.94e-146: 421: 32.74		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		667977 SPB3_HUMAN (48-420): 1.62e-144: 418: 30.95		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		344119 ANT3_HUMAN (10-420): 4.2e-140: 410: 32.14		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00
+	Hs
		403564 HEP2_HUMAN (53-423): 2.56e-50: 179: 32.11		UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00