HitPredict

Interactor 1: ANGT (P01015)
Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4]
Gene: Agt

Interactor 2: AGTRA (P25095)
Type-1 angiotensin II receptor A (Angiotensin II type-1 receptor A) (AT1 receptor A)
Gene: Agtr1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 7622467
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001568 - blood vessel development
GO:0001819 - positive regulation of cytokine production
GO:0001822 - kidney development
GO:0001991 - regulation of systemic arterial blood pressure by circulatory renin-angiotensin
GO:0002018 - renin-angiotensin regulation of aldosterone production
and 20 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 477
Rn

1 359
+ Mm
+ Hs
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+ Hs
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+ Hs

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Last updated: 15 Jul 2024