Interactor 1: A2MG (P01023)
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)
Gene: A2M

Interactor 2: ELNE (P08246)
Neutrophil elastase (EC 3.4.21.37) (Bone marrow serine protease) (Elastase-2) (Human leukocyte elastase) (HLE) (Medullasin) (PMN elastase)
Gene: ELANE

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 19506020
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains A2M_recep~Trypsin, MG2~Trypsin
Common GO terms GO:0002020 - protease binding
GO:0002438 - acute inflammatory response to antigenic stimulus
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0062023 - collagen-containing extracellular matrix
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1474
Hs

1 267
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024