Interactor 1: A2MG (P01023)
Alpha-2-macroglobulin (Alpha-2-M) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5)
Gene: A2M

Interactor 2: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.80 0.514

The method score is based on:

Property Details
Experiments 10652313
Identification Methods x-ray crystallography
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains A2M_BRD~Ldl_recept_a
Common GO terms -
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1474
Hs

1 4544
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024