Interactor 1: KNG1 (P01042)
Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain; T-kinin (Ile-Ser-Bradykinin); Bradykinin (Kallidin I); Lysyl-bradykinin (Kallidin II); Kininogen-1 light chain; Low molecular weight growth-promoting factor]
Gene: KNG1

Interactor 2: ACE2 (Q9BYF1)
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
Gene: ACE2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 10969042, 11815627
Identification Methods protease assay
Interaction Type protein cleavage

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0005886 - plasma membrane
GO:0008270 - zinc ion binding
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 644
Hs

1 805
+ Hs

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Last updated: 15 Jul 2024