HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 197
+	Hs
		345406 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		547789 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Mm
		562979 ATF2_MOUSE (4-293): 1.84e-28: 117: 18.62		TLE1_MOUSE (2-197): 2.15e-101: 310: 63.00
+	Hs
		579198 ATF3_HUMAN (131-215): 4.23e-25: 102: 43.53		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		862615 FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		568089 JUND_HUMAN (112-215): 1.79e-13: 72.8: 20.00		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50