HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: STK40 (Q8N2I9)
Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)
Gene: STK40

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.720

Property	Details
Experiments	26186194, 25609649, 28514442, 33961781, 35140242
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 435
+	Hs
		345337 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		MARK3_HUMAN (3-433): 6.07e-121: 370: 19.55
+	Hs
		548254 FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		579357 ATF6A_HUMAN (4-318): 1.09e-31: 128: 14.03		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		548318 FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		862625 FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		566775 JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		402242 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		STK40_HUMAN (1-435): 7.15e-121: 360: 100.00
+	Hs
		345527 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		345378 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		AAPK2_HUMAN (162-379): 1.47e-24: 107: 31.36
+	Hs
		871409 Q6FG41_HUMAN (1-380): 1.68e-84: 263: 100.00		AAPK2_HUMAN (162-379): 1.47e-24: 107: 31.36
+	Hs
		548261 FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		579370 ATF6A_HUMAN (4-318): 1.09e-31: 128: 14.03		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		548326 FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		862631 FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	Hs
		566786 JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31