HitPredict

Interactor 1: FOS (P01100)
Protein c-Fos (Cellular oncogene fos) (Fos proto-oncogene, AP-1 transcription factor subunit) (G0/G1 switch regulatory protein 7) (Proto-oncogene c-Fos) (Transcription factor AP-1 subunit c-Fos)
Gene: FOS

Interactor 2: TRI33 (Q9UPN9)
E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RET-fused gene 7 protein) (Protein Rfg7) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)
Gene: TRIM33

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070412 - R-SMAD binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 1127
+	Hs
		402629 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		TRI33_HUMAN (1-1127): 0: 679: 100.00
+	Hs
		170197 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		TIF1A_HUMAN (106-1127): 7.13e-146: 467: 44.94
+	Hs
		170242 FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61		TIF1A_HUMAN (106-1127): 7.13e-146: 467: 44.94
+	Hs
		345343 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		PML_HUMAN (83-635): 9.83e-61: 226: 17.01
+	Hs
		345507 FOS_HUMAN (1-380): 1.68e-84: 263: 100.00		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		548258 FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		1219912 BACH2_HUMAN (14-307): 4.1e-34: 136: 13.65		TRI42_HUMAN (112-581): 7.66e-59: 218: 14.95
+	Hs
		547715 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		PML_HUMAN (83-635): 9.83e-61: 226: 17.01
+	Hs
		547833 ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		1082500 HLF_HUMAN (3-202): 5.37e-30: 118: 20.00		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		974401 CREM_HUMAN (2-188): 4.21e-26: 109: 18.85		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		862628 FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		566778 JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		401478 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		PML_HUMAN (83-635): 9.83e-61: 226: 17.01
+	Hs
		402304 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		579220 ATF3_HUMAN (131-215): 4.23e-25: 102: 43.53		CBP_HUMAN (517-1061): 4.54e-59: 225: 15.06
+	Hs
		973605 CREB5_HUMAN (92-233): 1.13e-24: 107: 19.01		TRI42_HUMAN (112-581): 7.66e-59: 218: 14.95
+	Hs
		734601 CREB5_HUMAN (92-233): 1.13e-24: 107: 19.01		TRI23_HUMAN (91-479): 1.27e-59: 217: 16.20
+	Hs
		401940 JUN_HUMAN (48-215): 1.19e-23: 102: 16.47		TIF1B_HUMAN (631-1105): 6.36e-25: 114: 18.20